Sustained release dextroamphetamine (15-30 mg but not 30-60 mg) improved retention in patients with cocaine dependence.

Intervention Patients were allocated to dextroamphetamine sulphate, 15 mg for 28 days then doubled to 30 mg for 56 days {n=47}†; dextroamphetamine sulphate, 30 mg for 28 days and then doubled to 60 mg for 56 days {n=46}†; or to placebo {n=35}†. Patients received dextroamphetamine sulphate sustained release regimen once within 2 hours of awakening, and once 6 hours later. Dosing was supervised in the clinic only on the 2 visit days each week. Patients also received behavioural therapy once weekly.